Take 2 Slugs In The Gut And Call Me In The Morning
Vioxx was a billion dollar drug. A wonder that was handed to Merck on a platter from academic research. Vioxx wasn't one of the so-called breakthroughs that big pharm has to lose billions of dollars trying to develop. Professor Xie at Brigham Young U. handed the drug industry everything they needed, almost on a platter, with his paper "Xie WL, et al. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991;88(7):2692-6."
From there the drugs Celebrex and Vioxx were developed to target the cox-2 enzyme. Clinical trials almost took longer then development. They were hailed as a wonder and since it didn't take decades to develop the drug companies turned a profit quickly.
Until they started killing people. What looks like tens of thousands of people in a year.
Guns kill 12,000 Americans each year. It looks like doctors, the FDA and the legal pharmaceutical industry kill 4 times more Americans then guns. It's no wonder the American Medical Association is big on supporting gun control. They don't like the competition.